Paddy Lowe, who has been on an extended leave of absence since 5 March, will be leaving Williams and will step down from the board of directors with immediate effect.
Paddy Lowe said: “After a period of careful reflection I have reached the decision that I will not return to work at Williams.
“I wish all my previous colleagues the very best to meet the challenges ahead, which I am sure they will do. I would especially like to thank the Williams fans who are so supportive.”
Claire Williams said: “We understand and respect the decision Paddy has reached and wish him well for the future“.